Clinical Response of EXTOR (Amlodipine/Valsartan) in Newly Diagnosed Hypertensive Patients.
Recruiting now
Conditions studied: Hypertension
In brief
The American College of Cardiology/American Heart Association hypertension guidelines recommend treatment initiation with dual antihypertensive therapy in adults with stage 2 hypertension (corresponding to grade 1 and 2 in the ESH classification) and an average BP \>20/10 mm Hg above target. Amlodipine and valsartan are two of the most commonly prescribed medications for the treatment of hypertension (high blood pressure). In Pakistan multiple studies were conducted on Hypertension and use of Single Pill Combination in uncontrolled Hypertension. However, no study was conducted to assess the role of Single Pill Combination (SPC) like Amlodipine and Valsartan in newly diagnosed hypertension and to assess their quality of life by patients' satisfaction with their medication after managing the hypertension with the SPC.
Key facts
- Study ID
- NCT06625346
- Run by
- The Searle Company Limited Pakistan
- People needed
- 420
- Starts
- 2024-09-28
- Expected to finish
- 2025-09-15
- Last updated by the study team
- 2025-05-15
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patient with a clinical history of Hypertension (systolic blood pressure greater than or equal to 140 mmHg or a diastolic blood pressure greater than or equal to 90 mmHg) and never had antihypertensive treatment.
- Patient aged ≥18 and ≤70 years inclusive of either sex.
- Patient with ability to understand and sign written informed consent form.
You may not qualify if…
- • Patients with already on antihypertensive treatment or secondary hypertension
- Pregnant women or nursing mothers
- Patients with acute illnesses or psychiatric diagnosis
- Known hypersensitivity to Extor product, the metabolites, or formulation excipients.
- Treated with Extor to evaluate safety as per approved prescribing information for Extor in Pakistan.
Where it is running
- Kuwait Teaching Hospital — Peshawar, KPK, Pakistan (enrolling)
- National Medical Centre — Karachi, Pakistan (enrolling)
Full record on ClinicalTrials.gov
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