A Study to Evaluate the Effect of Food, Formulation, and a Proton Pump Inhibitor (PPI) on Calderasib (MK-1084) in Healthy Adult Participants (MK-1084-003)

Completed · Phase 1

Conditions studied: Healthy

In brief

The purpose of this study is to evaluate the effect of food, formulation, and a PPI on the levels of calderasib in a person's body over time.

Key facts

Study ID

NCT06619314

Run by

Merck Sharp & Dohme LLC

People needed

56

Starts

2023-09-20

Expected to finish

2023-11-25

Last updated by the study team

2026-02-11

Who can join

Age: 19 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Continuous non-smoker who has not used nicotine- and tobacco-containing products for at least 3 months prior to the first dosing.
• Medically healthy with no clinically significant medical history.

You may not qualify if…

• Has a history of cancer.
• Has had major surgery and/or donated or lost significant volume of blood.

Where it is running

• Celerion (Site 0001) — Lincoln, Nebraska, United States

Full record on ClinicalTrials.gov

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