Physical Activity Guarantees Bone Density.

Recruiting now · Not applicable

Conditions studied: Osteoporosis, Osteopenia

In brief

Bone tissue is crucial for overall health and quality of life, but it undergoes constant internal remodeling, leading to osteoporosis, a widespread bone disease. Regular physical activity can improve bone mineral density (BMD) and prevent osteoporosis. Studies have shown that premenopausal women with regular physical activity have greater BMD. Diagnosing bone resorption is essential, and dual-energy X-ray absorptiometry tests (DXA) and circulating microRNAs (miRNAs) may offer more prognostic potential than conventional markers. The gut microbiome may also regulate bone metabolism, with metabolites like trimethylamine N-oxide (TMAO) playing a role. A project aims to promote systematic physical activity to improve BMD and well-being, support societal mobilization, and conduct preventive examinations for osteoporosis risk. Implementing systematic prevention is important not only for health but also for reducing social and financial costs associated with osteoporosis and associated fractures.

Key facts

Study ID

NCT06606769

Run by

Poznan University of Physical Education

People needed

300

Starts

2024-09-13

Expected to finish

2027-06-30

Last updated by the study team

2024-10-10

Who can join

Age: 50 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• women

You may not qualify if…

• diagnosed osteoporosis

Where it is running

• Poznan University of Physical Education — Poznan, Poland (enrolling)

Full record on ClinicalTrials.gov

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