Predictors of Axial Pain Improvement After Anterior Cervical Discectomy and Fusion

Recruiting now

Conditions studied: Neck Pain, Cervical Spondylosis, Cervical Disc Disease

In brief

Neck pain is a common, multifactorial condition. In the case of degenerative cervical spinal disease, it can result from changes in the intervertebral discs, muscles, intervertebral joints, or sagittal imbalance. Anterior cervical discectomy and fusion (ACDF) is a currently widely accepted procedure for treating cervical degenerative spine disease, with a high patient satisfaction rate. In the current state of knowledge, it is not used for treating axial neck pain, but rather in cases of discopathy causing spinal myelopathy or cervical radiculopathy, in which neck pain often coexists or predominates. The current literature provides ample evidence of the significant effect of ACDF in improving axial neck pain in the conditions mentioned previously. However, little information exists on which patients achieve improvement. The aim of this prospective study is to analyze the outcomes of ACDF in patients with neck pain and to identify predictors of reduction in axial neck pain after ACDF.

Key facts

Study ID

NCT06601634

Run by

Medical University of Warsaw

People needed

60

Starts

2024-11-17

Expected to finish

2027-12-01

Last updated by the study team

2025-03-26

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ability to provide informed consent
• Patients who are qualified for one- or two-level ACDF for the treatment of degenerative cervical pathology

You may not qualify if…

• Previous cervical spine surgery
• Previous cervical spine trauma
• Other diseases causing neck pain include rheumatoid arthritis, lupus, polymyalgia rheumatica, myositis, seronegative inflammatory diseases, and fibromyalgia
• Drug abuse
• Myelopathy
• Spinal infection
• VAS neck pain score less than 3 (Inability to achieve an MCID which is calculated as 2.5 for the VAS scale)

Where it is running

• Department of Orthopaedics, J. Dietl Specialist Hospital — Krakow, Lesser Poland Voivodeship, Poland (enrolling)
• Department of Neurosurgery, Medical University of Warsaw — Warsaw, Masovian Voivodeship, Poland (enrolling)

Full record on ClinicalTrials.gov

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