Chlorhexidine Lavage for Recurrent Urinary Tract Infection
Running, not enrolling · Phase 4
Conditions studied: Urinary Tract Infections, Recurrent Urinary Tract Infection
In brief
A two-arm randomized control trial evaluating rates of urinary tract infection in post-menopausal women on vaginal estrogen with recurrent urinary tract infections.
Key facts
- Study ID
- NCT06598514
- Run by
- Oregon Health and Science University
- People needed
- 136
- Starts
- 2024-12-23
- Expected to finish
- 2026-06-01
- Last updated by the study team
- 2026-01-15
Who can join
Age: 55 and older, up to 89. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Post-menopausal female between age 55 and 89
- No post-menopausal bleeding
- Diagnosis of recurrent urinary tract infection (UTI) in the electronic health record or as two culture proven UTIs in 6 months or three culture proven UTIs in 12 months
- At least one UTI in the 6 months prior to entering the study
- Asymptomatic for UTI symptoms at the time of enrollment.
- On vaginal estrogen therapy for at least 6 weeks prior to enrollment
- Ready access to email and internet
You may not qualify if…
- Recent prophylactic antibiotic use (washout period of 4 weeks)
- Neurogenic bladder
- Diagnosis of urinary retention
- Uncorrected Stage III-IV prolapse
- Indwelling catheter or need for intermittent self-catheterization
- History of complicated UTIs
- History of interstitial cystitis or bladder pain syndrome
- History of fecal incontinence/accidental bowel leakage
- Greater than 14 bowel movements per week
- Non-English speaking
- Allergy to chlorhexidine gluconate
- Inability to utilize vaginal estrogen therapy
- Recent urogynecological or urologic surgery (<12 weeks)
Where it is running
- Oregon Health & Science University — Portland, Oregon, United States
Full record on ClinicalTrials.gov
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