PEEP Titration and Lung Recruitment Potential Assessed by 3D EIT
Recruiting now
Conditions studied: ARDS, Respiratory Failure
In brief
In a population of ARDS patients, we explore the influence of different PEEP levels on regional ventilation distribution, ventilation homogeneity, and the center of ventilation, optimal PEEP and lung recruitment potential as well as the extent of lung collapse and overdistension as detected by 3D-EIT.
Key facts
- Study ID
- NCT06594601
- Run by
- Peking Union Medical College Hospital
- People needed
- 50
- Starts
- 2024-01-01
- Expected to finish
- 2025-12-31
- Last updated by the study team
- 2024-09-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- patients on mechanical ventilation.
- Diagnosis of ARDS was based on the Berlin definition
- lung recruitment potential assessment and PEEP titration was proper for the ARDS patients determined by the attending doctor
You may not qualify if…
- Under 18 years of age.
- Pregnant women;
- Ribcage malformation
- Any contraindication to the use of EIT (e.g. automatic implantable cardioverter defibrillator, and implantable pumps).
- Hemodynamic instability, unable to tolerate high PEEP;
- High-risk individuals with pneumothorax, mediastinal emphysema, etc.
Where it is running
- Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, — Beijing, Beijing Municipality, China (enrolling)
Full record on ClinicalTrials.gov
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