TACE With Thermosensitive Nanogel Versus Embosphere for HCC
Recruiting now · Not applicable
Conditions studied: Unresectable Hepatocellular Carcinoma
In brief
To verify the safety and efficacy of TACE withThermosensitive Nanogel Embolic Agent for HCC.
Key facts
- Study ID
- NCT06593964
- Run by
- Zhongda Hospital
- People needed
- 188
- Starts
- 2024-09-10
- Expected to finish
- 2026-04-30
- Last updated by the study team
- 2024-09-19
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Chinese Liver Cancer Staging Scheme, stage IIb-Illa, as well as those with stage Ia-Ila HCC, unsuitable or unwilling to undergo surgical resection, transplantation, or ablation;
- Liver function status: Child-Pugh A or B
- Eastern Cooperative Oncology Group score: 0-2 points;
- With at least one measurable, unembolized liver tumor lesion (1-10 cm) ;
- Willing to participate in this trial and sign the informed consent.
You may not qualify if…
- The target lesion has been embolized before or require combined with other treatment(s);
- Diffuse or with extrahepatic metastasis;
- Coagulation dysfunction (PT prolonged beyond the upper limit of normal for 3 seconds);
- Severe renal dysfunctions (creatinine clearance rate <30 ml/min);
- Severe liver dysfunctions (alanine aminotransferase or aspartate aminotransferase exceeding the upper limit of normal by 5 times);
- Main portal vein was completely occluded and no collateral blood supply was established;
- With uncorrectable arteriovenous fistula or portal vein fistula;
- Severe cachexia or hepatic encephalopathy;
- With active infection;
- Significant reductions in white blood cells or platelets (white blood cells<3.0x109/L, platelets<50x109/L) that cannot be corrected;
- Pregnant or lactating women;
- Difficulty in selective catheterization;
- With the severe risk of non-target embolization;
- Severely allergic to contrast agents or the embolic materials;
- Participating in ongoing trial;
- Unsuitable judged by the investigator.
Where it is running
- Gao-Jun Teng — Nanjing, China (enrolling)
Full record on ClinicalTrials.gov
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