A Bundled Intervention
Recruiting now · Phase 1/Phase 2
Conditions studied: Opioid Use Disorder, Opioid Overdose
In brief
Opioid overdose deaths have reached historically high records in the United States and are particularly concentrated among patients after emergency department (ED) discharge. Evidence-based treatment modules to reduce repeat opioid overdose and mortality are lacking in this patient population. A bundled intervention is proposed, including telehealth, peer support specialist, buprenorphine, and linkage for definitive care, that is designed to increase treatment uptake in this patient population post-ED discharge, reduce repeat opioid overdoses, and end overdose deaths.
Key facts
- Study ID
- NCT06593093
- Run by
- University of Alabama at Birmingham
- People needed
- 190
- Starts
- 2025-02-13
- Expected to finish
- 2030-11-30
- Last updated by the study team
- 2026-02-23
Who can join
Age: 19 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- discharged from the ED and inpatient settings at the UAB hospital
- 19 years or older (the age of majority in Alabama);
- diagnosis of OUD and experiencing opioid overdose in the last 12 months;
- prescribed buprenorphine in the ED and willing to continue buprenorphine post-ED discharge;
- English speaking;
- not actively psychotic and suicidal, or cognitively impaired.
- Patients who are admitted to the hospital from the ED will be eligible for enrollment.
You may not qualify if…
- living in a restricted environment (e.g., prison or jail facility, etc.);
- currently enrolled in other clinical studies;
- anticipated to take other prescribed opioids except buprenorphine for a medical condition longer than three months;
- known allergic reaction to buprenorphine;
- critically ill or injured;
- females with pregnancy (they are anticipated to request a higher level of care).
- living outside of Alabama
Where it is running
- UAB — Birmingham, Alabama, United States (enrolling)
Full record on ClinicalTrials.gov
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