Brain Activity, Cognitive Function, and Walking Ability in Parkinson's Disease

Recruiting now

Conditions studied: Healthy Older Adults, Parkinson Disease

In brief

The dual-task automated walking performance in people with Parkinson\'s disease (PD) is affected by their gait disturbances and impaired executive functions. Currently, the relationship between brain activity related to inhibitory control, executive functions, and dual-task walking performance in people with PD is not well understood. Therefore, this study aims to investigate the significance of different executive function domains on gait stability in healthy older adults and people with PD; whether brain activation related to inhibitory control is associated with gait stability in healthy older adults and people with PD.

Key facts

Study ID

NCT06588920

Run by

National Yang Ming Chiao Tung University

People needed

70

Starts

2024-10-09

Expected to finish

2027-08-31

Last updated by the study team

2026-03-24

Who can join

Age: 40 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Diagnoses of idiopathic Parkinson disease
• Stable dopaminergic medicine ≥ 2 weeks
• Able to walk 10 meters without aid
• Mini-Mental Status Examination ≥ 24 points
• No uncorrected visual or auditory disorders
• Education at least junior high school
• No other disease may affect balance

You may not qualify if…

• Other medical diagnoses of neurological, musculoskeletal, or cardiopulmonary disorders
• History of brain surgery (e.g. deep brain stimulation)

Where it is running

• National Yang Ming Chiao Tung University — Taipei, Taiwan (enrolling)
• National Yang Ming Chiao Tung University — Taipei, Taiwan (enrolling)

Full record on ClinicalTrials.gov

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