PRospective Observation on CErebral microvaScular Structure and Function
Recruiting now
Conditions studied: Cerebral Microvascular Dysfunction, Cerebral Small Vessel Diseases, Cognitive Dysfunction, Cerebrovascular Disorders, Cardiovascular Diseases, Population
In brief
This is a population-based prospective cohort study, aiming to assess the prevalence, distributional characteristics, and dynamic change of cerebral small vessel dysfunction in a Chinese community population using advanced vascular imaging techniques; meanwhile to investigate the effect of vascular risk factors on cerebral small vessel dysfunction, cardiovascular and cerebrovascular diseases, cognitive dysfunction, and mortality.
Key facts
- Study ID
- NCT06579677
- Run by
- Beijing Tiantan Hospital
- People needed
- 3500
- Starts
- 2024-10-18
- Expected to finish
- 2032-10-01
- Last updated by the study team
- 2025-01-06
Who can join
Age: 50 and older, up to 75. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Community-dwelling adults aged 50-75 years;
- Registered Beijing household residents or residents who can be followed up stably in their own communities for a long period;
- Subjects with written informed consents.
You may not qualify if…
- Residents with moderate to severe disabilities (MRS ≥3), mental illness, stroke, dementia, and other serious neurological disorders (e.g., encephalitis, Parkinson's disease, epilepsy, brain tumors, and rare genetic diseases of the nervous system);
- Life expectancy of ≤4 years due to serious diseases such as end-stage cancer;
- Contraindications to magnetic resonance imaging such as implanted devices (e.g., pacemakers, defibrillators, and others);
- Residents who are participating in other studies.
Where it is running
- Beijing Daxing District People Hospital — Beijing, Beijing Municipality, China (enrolling)
- Beijing Tiantan Hospital — Beijing, Beijing Municipality, China
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.