Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy
Recruiting now
Conditions studied: B-ALL, Hematologic Malignancy, Solid Tumor
In brief
This study is being done to learn more about the short-term and long-term side effects of CAR-T cell therapy. Specifically, researchers want to know how often patients get infections, have delays in recovering blood cell counts and/or have damage to the nervous system.
Key facts
- Study ID
- NCT06579469
- Run by
- St. Jude Children's Research Hospital
- People needed
- 100
- Starts
- 2026-01-20
- Expected to finish
- 2029-03-01
- Last updated by the study team
- 2026-06-18
Who can join
Age: any, up to 30. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Participants must have received an initial systemically-administered CAR T cell infusion within the last 1-3 months (+/- 14 days).
- Initial infusion is defined as the first administration of a CAR T cell product the participant has not previously received OR receipt of a CAR T cell product previously received after an interval allogeneic HSCT.
- Age ≤ 30 years at CAR T cell infusion.
You may not qualify if…
- Active malignancy other than the disease under study.
- Planned consolidative HSCT within 3 months post CAR T cell infusion.
- Received or planned additional disease directed therapy post CAR T cell infusion.
- Inability or unwillingness of research participant or legal guardian/representative to give written informed consent.
Where it is running
- Childrens Hospital of Colorado — Aurora, Colorado, United States (enrolling)
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States (enrolling)
- St. Jude Children's Research Hospital — Memphis, Tennessee, United States (enrolling)
- Primary Children's Hospital — Salt Lake City, Utah, United States (enrolling)
- Seattle Childrens Hospital — Seattle, Washington, United States (enrolling)
- Children's Hospital of Wisconsin. — Milwaukee, Wisconsin, United States (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.