ASSESS ALL ALS Study
Recruiting now
Conditions studied: Amyotrophic Lateral Sclerosis
In brief
The ALL ALS Clinical Research Consortium is establishing research to collect a wide range of samples, clinical information and measurements from Amyotrophic Lateral Sclerosis (ALS) symptomatic, ALS gene carriers and control cohorts. This consortium is being funded by the National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS) and managed by two clinical coordinating centers (CCC) at Barrow Neurological Institute and Massachusetts General Hospital. The clinical sites are distributed across the country, and led by a group of collaborative principal investigators. Once data and samples are collected and harmonized, it will be made available to research community for future research into ALS and related neurological diseases. ASSESS protocol is specific for symptomatic ALS and control participants. This protocol includes both on-site and off-site(remote) participants. The participants will be followed for 24 months (2 years), and will include collection of medical history, clinical outcomes, and blood samples once in 4 months. Additionally, the participants will complete patient reported outcomes and speech recordings once a month. Participants who are coming into clinic may also provide optional Cerebrospinal Fluid (CSF) samples.
Key facts
- Study ID
- NCT06578195
- Run by
- St. Joseph's Hospital and Medical Center, Phoenix
- People needed
- 2000
- Starts
- 2024-07-25
- Expected to finish
- 2029-07-25
- Last updated by the study team
- 2026-07-30
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
Where it is running
- University of Alabama Birmingham — Birmingham, Alabama, United States (enrolling)
- Barrow Neurological Institute — Phoenix, Arizona, United States (enrolling)
- University of California, Irvine — Irvine, California, United States (enrolling)
- University of California San Diego — La Jolla, California, United States (enrolling)
- University of California, Los Angeles — Los Angeles, California, United States (enrolling)
- University of California, San Francisco — San Francisco, California, United States (enrolling)
- University of Colorado Anschutz Medical Campus — Aurora, Colorado, United States (enrolling)
- Hospital For Special Care — New Britain, Connecticut, United States (enrolling)
- Georgetown University — Washington D.C., District of Columbia, United States (enrolling)
- Nova Southeastern University — Davie, Florida, United States (enrolling)
- Mayo Clinic — Jacksonville, Florida, United States (enrolling)
- Saint Alphonsus Regional Medical Center — Boise, Idaho, United States (enrolling)
- Northwestern University — Chicago, Illinois, United States (enrolling)
- Synapticure (Remote Participation Only) — Chicago, Illinois, United States (enrolling)
- Indiana University — Indianapolis, Indiana, United States (enrolling)
- John Hopkins University — Baltimore, Maryland, United States (enrolling)
- Nih/Ninds — Bethseda, Maryland, United States (enrolling)
- Massachusetts General Brigham — Boston, Massachusetts, United States (enrolling)
- University of Michigan — Ann Arbor, Michigan, United States (enrolling)
- Henry Ford Health — Detroit, Michigan, United States (enrolling)
- University of Minnesota — Minneapolis, Minnesota, United States (enrolling)
- Washington University — St Louis, Missouri, United States (enrolling)
- University of Nebraska Medical Center — Omaha, Nebraska, United States (enrolling)
- Dartmouth Hitchcock Medical Center — Lebanon, New Hampshire, United States (enrolling)
- Columbia University — New York, New York, United States (enrolling)
Full record on ClinicalTrials.gov
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