Effect of Procyanidins in Leaky Gut Repairing in IBD
Recruiting now · Not applicable
Conditions studied: Ulcerative Colitis in Remission
In brief
The goal of this clinical trial is to learn if the Grape Seed Extract Ecovitis, featuring low monomeric catechins content and a high concentration of oligo-polymeric procyanidins, could modulate the Gut Microbiota composition of Ulcerative Colitis patients during the remission phase. The main questions it aims to answer are: Does Ecovitis improve the microbiota composition in patients with Ulcerative colitis? Is the intestinal permeability affected? What about the variation in the quality of life? Participants will: Take 2 capsules/day of Ecovitis for eight weeks Visit the clinic two times for checkups, serum collection, and Questionaire.
Key facts
- Study ID
- NCT06576700
- Run by
- University of Padova
- People needed
- 25
- Starts
- 2024-06-15
- Expected to finish
- 2026-06-12
- Last updated by the study team
- 2024-09-19
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of UC confirmed by clinical, endoscopic and histopathological evidence. Disease in remission phase confirmed by clinical, endoscopic and histopathological evidence.
- Age between 18 and 75 years old
- Ability of subject to participate fully in all aspects of this clinical trial.
You may not qualify if…
- ● Patients that have active UC, determined by clinical, endoscopic and histopathological evidences
- Known diagnosis of CD, indeterminate colitis, ischemic colitis, radiation colitis, diverticular disease associated with colitis or microscopic colitis
- Positive stool culture for active C. difficile
- Pregnant women
- Patients under antibiotic and/or probiotic treatment within 10 days prior to Visit 1.
Where it is running
- Edoardo Vincenzo Savarino — Padua, Padua, Italy (enrolling)
Full record on ClinicalTrials.gov
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