Neurophysiological Changes After Perturbation-based Training in Older Adults

Recruiting now · Not applicable

Conditions studied: Falling, Community Dwelling Older Adults, Postural Stability, Brain Connectivity, Brain Structure

In brief

This is an assessor-blinded neurophysiological study. Participants will be randomly assigned to a perturbation-based training (PBT) or a walking (control) group. Changes in postural stability and neurophysiology in the brain following PBT compared to walking exercise without perturbation will be investigated.

Key facts

Study ID

NCT06573658

Run by

The Hong Kong Polytechnic University

People needed

88

Starts

2024-04-18

Expected to finish

2026-10-14

Last updated by the study team

2025-09-24

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Aged ≥ 60 years old
• Community-dwelling
• Right-handed
• Able to communicate effectively in Cantonese or Mandarin
• Able to walk independently on level ground for ≥ 30 minutes
• Abbreviated Mental Test (Hong Kong version) score ≥ 6

You may not qualify if…

• Metal implants (e.g. pacemaker, artificial cochlea)
• Uncorrected vision or hearing impairment
• Osteoporosis
• Hip or knee replacement within the last year
• Musculoskeletal, cardiovascular, mental, or neurological disorders (such as Parkinson's disease) which can affect MRI examination, balance control, or exercise participation.

Where it is running

• The Hong Kong Polytechnic University — Hong Kong, Hong Kong (enrolling)

Full record on ClinicalTrials.gov

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