Adult HMO Supplementation and the Gut Microbiome

Completed · Not applicable

Conditions studied: Healthy Adults

In brief

The goal of this study is to assess the impact of Layer Origin's SuperHMO prebiotic formulation on the healthy adult gut microbiome. Over the course of 30 days, intervention participants will take SuperHMO prebiotic formulation daily. Control participants will take a placebo daily. We will measure all participants\' gut microbiome using a gut health test before taking SuperHMO prebiotic or placebo and after 30 days of taking the supplement. We hypothesize that taking the SuperHMO prebiotic will improve gut health measurements such as the potential to produce short-chain fatty acids.

Key facts

Study ID

NCT06570330

Run by

Seeding Inc

People needed

32

Starts

2024-08-22

Expected to finish

2025-07-30

Last updated by the study team

2026-04-24

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Participants are between the ages of 18 and 40.

You may not qualify if…

• Participants cannot have taken prebiotic or probiotic supplements within 6 months of starting study. This includes prebiotic or probiotic powder or supplements with prebiotic or probiotic addition or multivitamin with probiotic addition. This does not include food with live probiotics in it like yogurt or kefir.
• Participants must not be pregnant or breastfeeding or trying to conceive within the study period.
• Participants must be residents of the United States with US postal service.
• Participants cannot have the following existing health conditions:
• Pre-existing gut conditions (IBD, Celiac's disease, Crohn's disease, SIBO)
• Immune or auto-immune conditions (Type 1 Diabetes, human immunodeficiency virus (HIV))
• Participants cannot be lactose intolerant or have an allergy to dairy products.
• Participants are excluded if they have received results from an at home microbiome stool test in the past 6 months. This does not include clinical workup such as culture or pathogen testing.
• Participants must agree not to take another prebiotic or probiotic supplement or an at-home test over the study period.
• Participants must have no known major dietary changes upcoming.

Where it is running

• Seeding Inc — Rockville, Maryland, United States

Full record on ClinicalTrials.gov

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