Genetic Testing for the Prevention of Cancer in American Indian Communities (JUNIPER Trial)

Recruiting now · Not applicable

Conditions studied: Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm

In brief

This clinical trial is studying the genetic changes in cells associated with different types of cancer in American Indian (AI) populations in the Southwest to improve cancer screening, precision prevention, and therapeutic intervention for individual in these communities. AI tribes have much lower rates of cancer screening, have more limited access to healthcare, are more often diagnosed at later stages of disease, and have the poorest outcomes in all types of cancer when compared to any other racial and ethnic group in the United States. Due to these significant cancer health disparities, AIs have been understudied and little is known about the molecular characterization of tumors arising in AIs. Undergoing genetic testing of tumors may improve cancer outcomes in AI participants and communities.

Key facts

Study ID

NCT06569316

Run by

Mayo Clinic

People needed

300

Starts

2024-09-27

Expected to finish

2027-08-31

Last updated by the study team

2026-07-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female adults >= 18 years of age
• Cancer patient undergoing active treatment or a cancer survivor
• Self-identify as American Indian

You may not qualify if…

• Unable to provide informed consent
• Individuals who are under 18 years of age
• Prisoners

Where it is running

• Mayo Clinic in Arizona — Scottsdale, Arizona, United States (enrolling)

Full record on ClinicalTrials.gov

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