An Investigational Study of BG-89894 Tablets in Participants With Advanced Solid Tumors
Stopped early · Phase 1
Conditions studied: Advanced or Metastatic MTAP-deleted Solid Tumors
In brief
This study is being done to learn more about a new drug called BG-89894 (previously known as SYH2039). Researchers want to see if the drug is safe, how well people can tolerate it, how it moves through the body, and whether it shows any early signs of helping to treat cancer. The information gathered may help guide how future studies are designed. The entire study is expected to last about four years. People who join the study may receive treatment for around six months and will be followed for about 12 months after their treatment ends. The study plans to enroll participants over a three-year period.
Key facts
- Study ID
- NCT06568614
- Run by
- BeOne Medicines
- People needed
- 29
- Starts
- 2024-10-12
- Expected to finish
- 2026-04-13
- Last updated by the study team
- 2026-05-12
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Sidney Kimmel Comprehensive Cancer At Johns Hopkins — Baltimore, Maryland, United States
- Washington University School of Medicine — St Louis, Missouri, United States
- Columbia University Irving Medical Center — New York, New York, United States
- Next Virginia — Fairfax, Virginia, United States
- Blacktown Cancer and Haematology Centre — Blacktown, New South Wales, Australia
- Cancer Research South Australia — Adelaide, South Australia, Australia
- St Vincents Hospital — Fitzroy, Victoria, Australia
- Linear Clinical Research — Nedlands, Western Australia, Australia
- Cancer Hospital Chinese Academy of Medical Sciences — Beijing, Beijing Municipality, China
- Beijing Cancer Hospital — Beijing, Beijing Municipality, China
- Beijing Tsinghua Changgung Hospital — Beijing, Beijing Municipality, China
- Guangdong Provincial Peoples Hospital Huifu Branch — Guangzhou, Guangdong, China
- Guangxi Medical University Cancer Hospital — Nanning, Guangxi, China
- The Fourth Hospital of Hebei Medical University — Shijiazhuang, Hebei, China
- Union Hospital of Tongji Medical College, Huazhong University of Science and Technology — Wuhan, Hubei, China
- Jiangsu Province Hospital — Nanjing, Jiangsu, China
- The First Hospital of China Medical University Hunnan Branch — Shenyang, Liaoning, China
- Shanghai Pulmonary Hospital — Shanghai, Shanghai Municipality, China
- West China Hospital, Sichuan University — Chengdu, Sichuan, China
- Tianjin Medical University Cancer Institute and Hospital — Tianjin, Tianjin Municipality, China
Full record on ClinicalTrials.gov
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