Preimplantation Genetic Testing for Aneuploidy (PGT-A) in Couples With Non-obstructive Azoospermia (NOA)

Running, not enrolling

Conditions studied: Non-obstructive Azoospermia, Male Infertility

In brief

Objective: To examine the rate of embryo aneuploidy in patients with non-obstructive azoospermia (NOA) who utilize in-vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) and compare live birth rates with the utilization of preimplantation genetic testing for aneuploidy (PGT-A) vs non PGT-A.

Key facts

Study ID

NCT06566599

Run by

Inception Fertility Research Institute, LLC

People needed

400

Starts

2024-08-19

Expected to finish

2027-04-01

Last updated by the study team

2026-04-16

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Couples who have undergone in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) with or without pre-implantation genetic testing for aneuploidy (PGT-A) at a fertility clinic in The Prelude Network (US sites only).
• Male partner has diagnosis of non-obstructive azoospermia or obstructive azoospermia.
• Male partner has undergone surgical sperm extraction.

You may not qualify if…

• not applicable

Where it is running

• Inception Fertility Research Institute — Houston, Texas, United States

Full record on ClinicalTrials.gov

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