Effectiveness of Asiaticoside as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis

Recruiting now · Phase 2/Phase 3

Conditions studied: Intracanal Medication

In brief

The objective of this study is to investigate \"clinically\" the effectiveness of Asiaticoside based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.

Key facts

Study ID

NCT06566508

Run by

Mansoura University

People needed

36

Starts

2023-11-20

Expected to finish

2025-03-03

Last updated by the study team

2024-08-22

Who can join

Age: 20 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Single-rooted with pulp necrosis and apical periodontitis.

You may not qualify if…

• Receiving antibiotic treatment within the preceding 3 months.
• Reporting systemic disease.
• Teeth that could not be isolated with rubber dam.
• Teeth with periodontal pockets deeper than 3 mm.

Where it is running

• Mansoura university — Al Mansurah, Egypt (enrolling)

Full record on ClinicalTrials.gov

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