STunning in Acute Myocardial Infarction - BAS

Recruiting now · Phase 4

Conditions studied: Myocardial Infarct

In brief

The objective of this trial is to examine the effect of immediate versus late administration of beta blockers, angiotensin converting enzyme inhibitors (ACEI), and sodium/glucose cotransporter 2 (SGLT2) inhibitors on echocardiographic parameters and biomarkers in subjects with ST-elevation myocardial infarction (STEMI)

Key facts

Study ID

NCT06562582

Run by

Vastra Gotaland Region

People needed

120

Starts

2025-01-06

Expected to finish

2027-12-31

Last updated by the study team

2025-06-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with STEMI who undergo primary PCI within 6 hours of symptom onset (Excluding prodromal symptoms)
• Informed consent

You may not qualify if…

• Killip class ≥ 3
• Chronic kidney disease with GFR < 25 ml/min/1.73 m2
• Pre-existing non-reversible cardiac dysfunction or heart failure
• Current treatment with any beta blocker, RAAS inhibitor or SGLT2 inhibitor
• Absolute or relative contraindication to any one of the study drugs that confers a risk of patient safety if the patient participates in the trial and adheres to the protocol-specified recommendations, per the assessment of the treating physician
• Life expectancy less than one year
• Pregnancy or women of childbearing potential who is not sterilized or is not using a medically accepted form of contraception

Where it is running

• Sahlgrenska University Hospital — Gothenburg, Sweden (enrolling)

Full record on ClinicalTrials.gov

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