ACL-R Opioid Sparing Study
Enrolling by invitation · Phase 3
Conditions studied: Anterior Cruciate Ligament Injuries
In brief
This is a randomized control trial to investigate the effectiveness of a multimodal opiate sparing analgesic regimen in controlling post-operative pain and potentially reduce post-operative opioid consumption in patients undergoing Anterior Cruciate Ligament Reconstruction (ACL-R).
Key facts
- Study ID
- NCT06561035
- Run by
- Campbell Clinic
- People needed
- 56
- Starts
- 2024-09-01
- Expected to finish
- 2026-06-01
- Last updated by the study team
- 2024-08-19
Who can join
Age: 14 and older, up to 85. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 14-85 years of age.
- Patients undergoing primary ACL-R with or without meniscus repair or meniscectomy, with or without chondroplasty.
- Patients weigh at least 90lbs at time of enrollment.
- Surgery scheduled at a Campbell Clinic Surgery Center (Midtown or Wolf River).
- Willing and able to provide written informed consent.
- Willing and able to cooperate with postoperative therapy.
- Speak and read fluent English.
You may not qualify if…
- Multiligament knee reconstruction.
- Pre-injury opioid consumption.
- Substance abuse disorder (illicit drug abuse, alcoholism, etc).
- Concomitant injuries or surgeries warranting pain medication (i.e. polytrauma patient).
- Chronic pain syndrome.
- Renal disease.
- Currently taking selective serotonin reuptake inhibitors and/or serotonin and norepinephrine reuptake inhibitors.
- Known sensitivity, allergy, or intolerance to medications within protocols.
- History of diabetes.
- Currently taking glucagon-like peptide 1 agonist.
- Female patient who is pregnant on day of surgery or becomes pregnant during study period.
Where it is running
- Campbell Clinic — Memphis, Tennessee, United States
Full record on ClinicalTrials.gov
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