Tracking Early Emergence of Sound Perception Impairments in FXS With Multimodal fNIRS/EEG- Infant

Recruiting now · Not applicable

Conditions studied: Fragile X Syndrome

In brief

Individuals with Fragile X Syndrome show differences in how they understand and learn language from infancy. They frequently have lifelong delays in speech and language as well. In addition, they experience other auditory symptoms, including being very sensitive to certain sounds as well as being more sensitive than others to loud sounds. The underlying brain activity for sound perception and speech learning in Fragile X is not well understood, especially in the infant and toddler years. This study uses behavioral assessment of speech and language abilities, neuroimaging, and hearing tests to understand how speech and hearing are different in children with Fragile X Syndrome.

Key facts

Study ID

NCT06560242

Run by

Children's Hospital Medical Center, Cincinnati

People needed

30

Starts

2022-10-31

Expected to finish

2027-03-01

Last updated by the study team

2026-07-10

Who can join

Age: 1 and older, up to 2. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Diagnoses of Fragile X Syndrome, Typical Development, or History of Premature Birth
• able to sit independently
• English is spoken at home

You may not qualify if…

• For all participants: no seizures in the past 6 months
• For typical development group and Fragile X group: not born prior to 32 weeks gestation

Where it is running

• Cincinnati Children's Hospital — Cincinnati, Ohio, United States (enrolling)

Full record on ClinicalTrials.gov

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