Median Versus Ulnar Nerve Quantitative Electromyography Neuromuscular Blockade Monitoring Comparison

Recruiting now

Conditions studied: Neuromuscular Blockade

In brief

Medications used to relax the muscles are used during surgery. The amount of muscle relaxation can monitored with devices that stimulate a specific nerve and evaluate the muscle response. The response to, and recovery from, medications that relax the muscles are best described for a nerve in the arm called the ulnar nerve. The investigators believe that other nerves in the arm, such as the median nerve, could be used to monitor the amount of muscle relaxation. The purpose of this study is to compare the muscle response at two different nerve sites after giving medications to relax the muscles. This study is going to measure the depth of muscle relaxation during surgery at two different sites. The muscle response to stimulation of the ulnar nerve (located in the arm) will be compared to the muscle response to stimulation of the median nerve (also located in the arm).

Key facts

Study ID

NCT06553131

Run by

Loma Linda University

People needed

32

Starts

2024-12-26

Expected to finish

2026-12-01

Last updated by the study team

2026-01-30

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults 18 - 75 years of age who are able to provide consent
• Scheduled for elective surgery requiring muscle relaxation, in a supine position under general anesthesia, with an anticipated duration of at least 1.5 hours

You may not qualify if…

• Contraindication to rocuronium use
• Comorbidities that may prolong the duration of neuromuscular blockade or alter pharmacodynamics and/or pharmacokinetics, such as:
• Neuromuscular disease
• Expected or known difficult airway
• Rocuronium allergy
• BMI < 18.5 or > 40
• History of adhesive allergy
• Upper extremity weakness, limb deformity, or absence of all or part of an upper limb
• Patients undergoing surgical procedures requiring cardiopulmonary bypass

Where it is running

• Loma Linda University Troesch Medical Center — Loma Linda, California, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.