The Application of Photosensitive Hydrogel in Intranasal Endoscopic Dacryocystorhinostomy

Recruiting now · Not applicable

Conditions studied: Chronic Dacryocystitis

In brief

To study the effect of Photosensitive hydrogel used for suture free anastomosis of lacrimal cyst and nasal mucoperiosteal flap in endoscopic nasal dacryocystostomy, and evaluate its adhesion to lacrimal cyst and nasal mucoperiosteal flap, promoting wound healing, forming a good anastomosis, preventing postoperative anastomosis and shortening operation time. Twenty patients with chronic dacryocystitis were randomly divided into photosensitive hydrogel group and suture group.Symptoms and nasal endoscopy were followed up 2, 6, and 12 weeks after surgery for both groups. And also adverse events were recorded at each follow-up.

Key facts

Study ID

NCT06551766

Run by

Eye & ENT Hospital of Fudan University

People needed

20

Starts

2023-03-01

Expected to finish

2024-12-31

Last updated by the study team

2024-08-13

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Voluntarily participate in this clinical study and sign the informed consent;
• Gender is not limited, age 18-75 years old;
• The patient had symptoms and signs of chronic dacryocystitis, and the results of lacrimal passage irrigation suggested that the lower rush and return or upper rush and lower return, accompanied by mucous or purulent discharge reflux;
• Lacrimal duct angiography suggests nasolacrimal duct obstruction without lacrimal canaliculi and/or duct obstruction.

You may not qualify if…

• Age < 18 or > 75 years old;
• Previous history of dacryocystonasal anastomosis;
• Abnormal coagulation function;
• Tumors of lacrimal passage, especially in patients with papilloma or malignant tumors;
• in the acute dacryocystitis attack stage;
• obvious scar constitution;
• Complicated with serious nasal diseases, such as severe allergic rhinitis, chronic rhinosinusitis and nasal polyps, acute suppurative rhinosinusitis, severe atrophic rhinitis, and severe deviation of nasal septum;
• Have serious heart, liver, kidney, lung and other basic diseases, can not tolerate general anesthesia;
• Distance from the hospital, postoperative review is not convenient;
• Participated in other clinical trials within the last 3 months;
• Any medical history that the investigator determines may interfere with the test results or increase the patient's risk.

Where it is running

• Eye & ENT Hospital of Fudan University — Shanghai, China (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.