Safe and Fast Radial Hemostasis Using Synergistic Strategies: SAFE & FAST Trial

Completed · Not applicable

Conditions studied: Cardiovascular Diseases, Bleeding, Arterial Puncture, Catheter Complications, Occlusion of Artery

In brief

The Safe and Fast Radial Hemostasis using Synergistic Strategies (SAFE \& FAST) trial is an interventional study aimed at reducing the incidence of radial artery occlusion (RAO) rebound bleeding, and the required compression time after transradial approach (TRA) procedures, which have become the default access for coronary procedures globally. The hypothesis is that combining lower-dose heparin and radial hemostasis with simultaneous ipsilateral ulnar artery compression could achieve these improved outcomes.

Key facts

Study ID

NCT06549842

Run by

Regional Hospital of Scranton

People needed

451

Starts

2024-08-15

Expected to finish

2026-02-20

Last updated by the study team

2026-03-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients referred for diagnostic transradial cardiac catheterization
• Age ≥ 18 years
• Ability to provide written informed consent

You may not qualify if…

• Absence of written informed consent
• Patients on long-term systemic anticoagulation therapy for a different indication
• Patients requiring a heparin dose of greater than 50 units per kilogram before, during, or after the procedure for any reason.
• Patients requiring greater than 6 French catheter access

Where it is running

• Regional Hospital of Scranton — Scranton, Pennsylvania, United States
• Apex Heart Institute — Ahmedabad, Gujarat, India

Full record on ClinicalTrials.gov

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