Sensory Synchronized Imaging and Neuromodulation

Starting soon · Not applicable

Conditions studied: Major Depressive Disorder

In brief

The purpose of this research study is to better understand the relationship between the type of brain stimulation used and how it changes brain activity in adult military Veterans. The goal is to use this understanding to develop new, personalized brain stimulation. The investigators evaluate brain changes from different types of transcranial magnetic brain stimulation (TMS).

Key facts

Study ID

NCT06548113

Run by

VA Office of Research and Development

People needed

250

Starts

2026-07-13

Expected to finish

2030-12-31

Last updated by the study team

2026-06-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Men and women, ages 18 years and up
• English speaking
• Military Veterans

You may not qualify if…

• Those with a contraindication for MRIs (e.g. implanted metal)
• History of head trauma with loss of consciousness
• History of seizures or on medications that substantially reduce seizure threshold
• Neurological or uncontrolled medical disease
• Active substance abuse
• Currently pregnant or breastfeeding

Where it is running

• VA Palo Alto Health Care System, Palo Alto, CA — Palo Alto, California, United States

Full record on ClinicalTrials.gov

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