The Effect of Melatonin Supplementation on Cumulus Cells and IVF Outcomes

Recruiting now · Not applicable

Conditions studied: Unrecognized Condition

In brief

This study investigates the effects of melatonin supplementation on cumulus cell gene expression and in vitro fertilization (IVF) outcomes in women over 35 years old. In the study group, patients will receive melatonin supplementation for at least two months prior to their IVF cycles. Cumulus cells will be collected after oocyte retrieval, and IVF outcomes will be assessed.

Key facts

Study ID

NCT06546774

Run by

Kaohsiung Veterans General Hospital.

People needed

200

Starts

2021-05-01

Expected to finish

2025-12-31

Last updated by the study team

2024-08-13

Who can join

Age: 35 and older, up to 45. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Age 35-45 years
• BMI 18-30 kg/m2
• planning to undergo IVF cycles

You may not qualify if…

• Primary ovarian insufficiency
• history of oophorectomy
• receiving oocyte donation
• Chromosome anomaly
• Congenital uterine anomaly
• Severe intrauterine adhesion
• Malignancy
• Using hormone therapy or supplements in recent 3 months

Where it is running

• Department of Obstetrics and Gynecology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan — Kaohsiung City, Taiwan (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.