Measuring Upper Airway Cross Sectional Areas During Residual Neuromuscular Blockade and After Reserval

Recruiting now

Conditions studied: Postoperative Residual Curarization, Airway Obstruction on Anaesthetic Emergence

In brief

In our study, the investigators sought to answer the question of how the retroglossal pharyngeal areas measured after extubation of patients compare to baseline (before muscle relaxation) values. The investigators also investigated how these areas change as a function of TOF ratios measured at extubation, thus looking for a correlation between residual muscle relaxant effect and airway area.

Key facts

Study ID

NCT06544980

Run by

Tamas Vegh, MD

People needed

20

Starts

2024-01-02

Expected to finish

2025-12-31

Last updated by the study team

2024-08-12

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age: 18-65 years;
• ASA 1-3;
• BMI 18.5-25 (normal body weight);
• men/women in equal proportion;
• duration of surgeries at least ≥ 30 minutes;
• intervention requiring intratracheal intubation;
• patients are in a supine position.

You may not qualify if…

• diseases affecting neuromuscular function (myopathies, severe liver and kidney failure);
• drugs affecting neuromuscular function (magnesium, aminoglycosides);
• difficult airway, expected difficult intubation;
• pregnancy (pregnancy test for women of childbearing age to rule out pregnancy we finish);
• breastfeeding;
• acute surgery;
• COPD
• glaucoma

Where it is running

• University of Debrecen — Debrecen, Hajdú-Bihar, Hungary (enrolling)

Full record on ClinicalTrials.gov

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