Harm Reduction for Smokers With Mental Illness

Recruiting now · Not applicable

Conditions studied: Tobacco Dependence

In brief

To compare the efficacy of e-cigarette (e-cig) provision with or without behavioral support (SWITCH IT) delivered via telehealth to reduce harm among smokers with MI who cannot quit smoking and are not ready to pursue cessation treatment, and to examine self-regulation (using e-cigs instead of cigarettes to cope with stress/distress and self-efficacy) as a potential mechanism for behavior change from SWITCH IT

Key facts

Study ID

NCT06543407

Run by

Dartmouth-Hitchcock Medical Center

People needed

250

Starts

2024-10-01

Expected to finish

2028-03-31

Last updated by the study team

2026-01-15

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• Currently residing in a nursing home;
• Current diagnosis of Asthma;
• Cognitive impairment (score <26 on the Telephone Interview for Cognitive Status (TICS);
• Current use of e-cigarettes (>once a week);
• Psychiatric instability (hospitalized in the past month);
• Current AND moderate to severe substance use disorder;
• Pregnant or planning to become pregnant;
• Use of any smoked products other than cigarettes;
• Current unstable medical illness making e-cigarette unsafe (e.g., recent heart attack, cancer);
• Participation in SWITCH IT pilot study.

Where it is running

• Seven Counties Services — Louisville, Kentucky, United States (enrolling)
• The Providence Center — Providence, Rhode Island, United States (enrolling)

Full record on ClinicalTrials.gov

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