A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers
Recruiting now
Conditions studied: Hepatocholangiocarcinoma, Fibrolamellar Carcinoma, Hepatic Epithelioid Hemangioendothelioma, Hepatoblastoma, Hepatic Neuroendocrine Carcinoma, Hepatic Carcinosarcomas, Hepatic Cystadenoma, Hepatic Leiomyosarcomas, Hepatic Angiosarcomas, Cholangiocarcinoma
In brief
The aim of this French multicenter retrospective study is to describ rare primary hepatic cancers clinical, histological and radiological features, to obtain a biological tumor and blood collection, and to evaluate the efficacy of treatments received in clinical practice in order to determine optimal therapeutic sequences. This retrospective cohort will be the backbone of future translational studies aimed at identifying new molecular, histological, circulating and radiological tumor biomarkers, potentially useful at every stage of diagnosis and prognostic or theranostic evaluation.
Key facts
- Study ID
- NCT06541652
- Run by
- Federation Francophone de Cancerologie Digestive
- People needed
- 150
- Starts
- 2024-03-26
- Expected to finish
- 2031-02-01
- Last updated by the study team
- 2025-08-05
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- 18 years of age or older,
- with histologically proven hepato-cholangiocarcinoma, fibrolamellar hepatocellular carcinoma, epithelioid hemangioendothelioma or hepatic angiosarcoma
- diagnosed after January 01, 2018 living or deceased at the time of registration in the cohort
- for living patients who have not objected to the research: (note of non-objection to be attached° agreeing to participate in ancillary studies must sign the biological consent form for participation in biological studies.
You may not qualify if…
- without social security
- No access to tumor block
Where it is running
- CHU Amiens picardie — Amiens, France (enrolling)
- Chu Angers — Angers, France (enrolling)
- Ch - Centresimone Veil de Beauvais — Beauvais, France (enrolling)
- CHR - Metz Thionville Hopital de Mercy — Metz, France (enrolling)
- Chu de Paris Saint Antoine — Paris, France (enrolling)
- AP - HP - Pitié Salpêtrière — Paris, France (enrolling)
- Centre Hospitalier de Perpignan — Perpignan, France (enrolling)
- Hopital Haut Leveque — Pessac, France (enrolling)
- Chu de Poitiers — Poitiers, France (enrolling)
- CH - Annecy Genevois — Pringy, France (enrolling)
- Chu Robert Debre — Reims, France (enrolling)
- Hopital Nord Chu Saint Etienne — Saint-Priest-en-Jarez, France (enrolling)
- Groupe Hospitalier Rance Emeraude — St-Malo, France (enrolling)
- Chu Rangueil — Toulouse, France (enrolling)
- Avicenne — Bobigny, France (enrolling)
- Centre Hospitalier — Calais, France (enrolling)
- Chu de Clichy Hopital Beaujon — Clichy, France (enrolling)
- Centre Hospitalier Universitaire Henri Mondor — Créteil, France (enrolling)
- CHU — Dijon, France (enrolling)
- Chu Grenobles Alpes — La Tronche, France (enrolling)
- Centre Hospital Universitaire de lille — Lille, France (enrolling)
- Longjumeau Ch Nord Essone — Longjumeau, France (enrolling)
- Ch Edouard Herriot — Lyon, France (enrolling)
- Centre Léon Berard — Lyon, France (enrolling)
- La Clinique de La Sauvegarde — Lyon, France (enrolling)
Full record on ClinicalTrials.gov
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