Respiratory Training in Friedreich's Ataxia

Completed · Not applicable

Conditions studied: Friedreich Ataxia

In brief

This is a prospective interventional study of patients with Friedreich's Ataxia that receive respiratory strength training for a period of 12 weeks with two research visits at the beginning and at the end of the study period. Visits include swallowing evaluation with fiberoptic endoscopic evaluation of swallowing, pulmonary function testing, surface electromyography and patient surveys.

Key facts

Study ID

NCT06539598

Run by

University of Florida

People needed

1

Starts

2024-08-29

Expected to finish

2025-08-07

Last updated by the study team

2025-11-03

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• confirmed genetic testing of Friedreich's Ataxia
• have an overall DIGEST score of 1 or higher based on FEES screening
• are able to perform pulmonary function testing

You may not qualify if…

• have been on antibiotics within 15 days prior to baseline screening.
• have been prescribed systemic corticosteroids or neuromuscular blocking agents within 15 days of the baseline screening
• have an allergy or contraindication to topical lidocaine or oxymetazoline
• have any other concurrent medical condition which, in the opinion of the investigators, would make the subject inappropriate to participate in testing or respiratory exercise

Where it is running

• Clinical Research Center — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.