Adding Polyphenol-rich Pulses to Daily Diet Improves Skin Health by Reshaping the Skin Microbiome

Recruiting now · Not applicable

Conditions studied: Healthy

In brief

Skin health is influenced by the microbiome, lipids, oxidative stress, inflammation, and UV exposure. A 12-week trial with 48 women aged 45-65 will test if polyphenol-rich pulses improve skin health by affecting these factors. Using a white rice control diet, the study will measure skin parameters and analyze correlations with changes in lipids and microbiome, potentially proving the benefits of pulses.

Key facts

Study ID

NCT06538415

Run by

University of Florida

People needed

50

Starts

2026-05-12

Expected to finish

2026-12-31

Last updated by the study team

2026-07-02

Who can join

Age: 45 and older, up to 65. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• BMI (18.5-29.9)
• Body weight ≥110 pounds
• Fitzpatrick skin type 1,2 and 3.

You may not qualify if…

• pregnancy
• breast-feeding
• impaired fasting glucose
• frequent alcohol use
• history of skin cancer
• sunbathing and the use of tanning bed, intake of vitamin/mineral supplements
• habitual high intake of fruits (≥ 2 cups daily)
• intake of medication that might influence the outcome of the study

Where it is running

• Food Science and Human Nutrition — Gainesville, Florida, United States (enrolling)

Full record on ClinicalTrials.gov

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