The Impact of Music Medicine on Preterm Brain Development and Behavior
Recruiting now · Not applicable
Conditions studied: Infant Development, Language Development, Prematurity, Stress
In brief
The investigators are conducting a two-site randomized control trial with the aim of defining the impact of music (M) without or with parent voice (MPV) on very preterm infants' acute and cumulative stress, intranetwork connectivity on term brain MRI, and language and other neurodevelopmental outcomes at two years corrected age. This is based on the hypothesis that infants in MPV arm are expected to experience the greatest benefit compared with infants receiving standard care.
Key facts
- Study ID
- NCT06536296
- Run by
- Brigham and Women's Hospital
- People needed
- 243
- Starts
- 2025-05-19
- Expected to finish
- 2031-03-01
- Last updated by the study team
- 2026-03-25
Who can join
Age: 0 and older, up to 1. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Very preterm infants born between 24+0 and 30+6 weeks' gestational age (GA) from 2 level III NICUs (Brigham and Women's Hospital, Boston, MA and Yale New Haven, CT)
- Infants who are medically stable per the clinical care team
You may not qualify if…
- Infants with major genetic or congenital anomalies known to be associated with developmental delay
- Infants with severe brain injury (such as intraparenchymal hemorrhage, severe white matter injury)
- Infants who are severely ill infants for whom MBI is not feasible
- Infants of parents who cannot complete questionnaires in English or Spanish.
Where it is running
- Brigham and Women's Hospital — Boston, Massachusetts, United States (enrolling)
- Yale New Haven Hospital — New Haven, Connecticut, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.