Influence of Human Albumin Supplementation on Kidney Dysfunction After Liver Transplantation
Recruiting now · Phase 4
Conditions studied: Liver Transplantation, Acute Kidney Injury
In brief
To verify whether albumin administration to achieve serum concentration above 30g/L (treated group) and its maintenance within plasmatic physiologic range (above 30 g/L) for five days diminishes rate of AKI at Day 7 after liver transplantation as compared to restrained albumin administration (when serum concentration is at 20 g/L or below (control)).
Key facts
- Study ID
- NCT06535945
- Run by
- Rennes University Hospital
- People needed
- 400
- Starts
- 2025-03-26
- Expected to finish
- 2028-04-26
- Last updated by the study team
- 2026-06-17
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Male and female subjects equal or above 18 yrs old.
- Recipients of primary liver allografts from a deceased donor (including after cardiac death) and as a single organ (liver only).
- Capability of understanding the purpose and risks of the study.
- Written informed consent
You may not qualify if…
- Fulminant hepatitis
- Kidney injury at baseline (Estimated Glomerular Filtration Rate < 50 ml/min in Modification of diet in renal disease-6) including hepatorenal syndrome
- Use of an induction agent Basiliximab at liver transplantation
- Protected person (adults legally protected, under judicial protection, guardianship, or supervision), person deprived of their liberty
Where it is running
- 08_CHRU de Tours Hôpital Trousseau — Chambray-lès-Tours, France (enrolling)
- 03_APHP Hôpital Beaujon — Clichy, France (enrolling)
- 04_CHU de Lille Hôpital Huriez — Lille, France (enrolling)
- 05_HCL Hôpital de la Croix Rousse — Lyon, France (enrolling)
- 06_CHU de Montpellier Hôpital St Eloi — Montpellier, France (enrolling)
- 02_CHU de Bordeaux - Hôpital Haut Leveque — Pessac, France (enrolling)
- 01_CHU de Rennes Hôpital Pontchaillou — Rennes, France (enrolling)
- 09_APHP Hôpital Paul Brousse — Villejuif, France (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.