NAD Supplementation and Vascular Health in PAD

Completed · Phase 1/Phase 2

Conditions studied: Peripheral Artery Disease

In brief

This pilot open-label clinical trial was designed to investigate whether 4-week supplementation with 1g daily NR impacts endothelial function in peripheral circulation, cerebrovascular hemodynamics, cognitive function in older adults with peripheral artery disease.

Key facts

Study ID

NCT06534944

Run by

University of Oklahoma

People needed

8

Starts

2023-02-27

Expected to finish

2024-12-30

Last updated by the study team

2026-04-06

Who can join

Age: 55 and older, up to 99. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• diagnosis of PAD
• intermittent claudication
• limited walking capacity

You may not qualify if…

• macologically uncontrolled type 2 diabetes, hypercholesterolemia, hypertension
• major depressive disorder
• current or prior cerebrovascular complications (including large vessel ischemic stroke with chronic functional impairment)
• neurodegenerative diseases

Where it is running

• University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.