Study on Multimodal Imaging and Molecular Imaging Techniques in Degenerative Dementia

Recruiting now

Conditions studied: Alzheimer Disease, Image

In brief

This project is a multicenter observational study that establishes a longitudinal cohort of patients with Alzheimer's disease and other dementias based on neuroimaging, molecular imaging, biological and digital markers to explore new solutions such as dementia disease mechanism, diagnosis, condition evaluation, and prognosis assessment.

Key facts

Study ID

NCT06534658

Run by

Ruijin Hospital

People needed

1000

Starts

2020-07-30

Expected to finish

2029-08-30

Last updated by the study team

2024-08-02

Who can join

Age: 50 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged ≥50 and ≤85 years old, male or female;
• Meet the diagnostic criteria for dementia or MCI;
• Neuropsychological score: MMSE 15-28 points, CDR ≤ 1 point; ④ Patients and their families are informed and sign the informed consent form

You may not qualify if…

• The presence of other neurological diseases that may cause brain dysfunction (such as depression, brain tumors, Parkinson's disease, metabolic encephalopathy, encephalitis, multiple sclerosis, epilepsy, brain trauma, normal intracranial pressure hydrocephalus, etc.);
• The presence of other systemic diseases that may cause cognitive impairment (such as liver dysfunction, renal dysfunction, thyroid dysfunction, severe anemia, folic acid or vitamin B12 deficiency, syphilis, HIV infection, alcohol and drug abuse, etc.);
• Suffering from a disease that makes it impossible to cooperate with cognitive examinations;
• The presence of contraindications to MRI;
• The presence of mental and neurological retardation;
• Refusing to draw blood;
• Refusing to sign the informed consent form.

Where it is running

• Chinese People's Liberation Army General Hospital — Beijing, Beijing Municipality, China (enrolling)
• First Affiliated Hospital of Zhejiang University School of Medicine — Hanzhong, Hangzhou, China (enrolling)
• Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine — Cangzhou, Hebei, China (enrolling)
• The Second Hospital of Hebei Medical University — Shijiazhuang, Hebei, China (enrolling)
• Qilu Hospital of Shandong University, Qingdao Branch — Qingdao, Shandong, China (enrolling)
• Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine — Shanghai, Shanghai Municipality, China (enrolling)
• Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine — Shanghai, Shanghai Municipality, China (enrolling)
• The First Affiliated Hospital of China Medical University — Shenyang, Shenyang, China (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.