Predicting Mortality in Kidney Transplant Recipients

Status unconfirmed

Conditions studied: Death

In brief

Accurately predicting kidney recipient risk of death has a crucial interest because of the organ shortage, the need to optimize allograft allocation by identifying high-risk patients who may not benefit from a transplant and improve the clinical decision-making after transplant to ensure that each patient survives as long as possible. However, according to a literature review the investigators performed, studies attempting to develop a kidney recipient death prediction model suffer from many shortcomings, including the lack of key risk factors, use of biased registry data, small sample size, lack of external validation in different countries and subpopulations, and short follow-up. The present study thus aimed to address these limitations and develop a robust, generalizable kidney recipient death prediction model.

Key facts

Study ID

NCT06531967

Run by

Paris Translational Research Center for Organ Transplantation

People needed

13000

Starts

2004-01-01

Expected to finish

2024-08-01

Last updated by the study team

2024-08-01

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult kidney recipients

You may not qualify if…

• Multi-organ transplantation
• Prior kidney transplant

Where it is running

• Department of Medicine, Mayo Clinic — Phoenix, Arizona, United States
• Bakar Computational Health Sciences Institute, University of California — San Francisco, California, United States
• Penn Transplant Institute, Hospital of the University of Pennsylvania — Philadelphia, Pennsylvania, United States
• Department of Nephrology and Renal Transplantation, University Hospitals Leuven — Leuven, Belgium
• Division of Nephrology, University Hospital Liège (CHU) — Liège, Belgium
• Necker hospital — Paris, France
• Saint-Louis hospital — Paris, France
• Tenon hospital — Paris, France
• Department of Nephrology and Organ Transplantation, Toulouse University Hospital — Toulouse, France
• Department of Nephrology and Clinical Immunology, University Hospital of Tours — Tours, France
• Leiden Transplant Center, Leiden University Medical Center — Leiden, Netherlands

Full record on ClinicalTrials.gov

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