Cardiovascular Response to Isometric BFR Exercise

Completed · Not applicable

Conditions studied: Blood Pressure

In brief

The goal of this interventional study is to evaluate the acute impact of isometric blood flow restriction (BFR) exercise on blood pressure and other cardiovascular functions in healthy young adult volunteers. The main question it aims to answer is: The investigators hypothesize that isometric BFR exercise with a wide-rigid cuff would lead to greater blood pressure and other cardiovascular responses and that these cardiovascular responses would be greater under isometric BFR exercise with narrow-elastic bands compared with the control condition (no cuff). Participants will perform isometric exercises in 3 laboratory visits with different exercise conditions) no cuff control 2) BFR with wide-rigid cuff 3) BFR with narrow-elastic band.

Key facts

Study ID

NCT06529068

Run by

Hirofumi Tanaka

People needed

21

Starts

2024-12-02

Expected to finish

2025-05-30

Last updated by the study team

2026-06-10

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Apparently healthy young adults aged between 18 - 40 years old and signed the informed consent.

You may not qualify if…

• Abnormal clotting times
• Acid-base imbalance/acidosis
• Arterial calcification
• Atherosclerotic vessels
• Cardiopulmonary conditions
• Diabetes
• Dialysis/central venous access
• General/local infection
• High intracranial pressure
• Hip, pelvis, or femur fracture
• History of venous thromboembolism
• Hypertension
• Immobility for greater than 48 hours in the past month
• Immobilizing cast
• Implanted medical device
• Lymphectomies
• Obesity
• Open fracture
• Open or unhealed soft tissue injuries
• Paralysis
• Peripheral vascular disease
• Pregnancy/postpartum
• Prior revascularization
• Renal compromise
• Severe crush injuries

Where it is running

• Cardiovascular Aging Research Laboratory — Austin, Texas, United States

Full record on ClinicalTrials.gov

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