Evaluating the Impact of Different Methods of HPV DNA Testing for Cervical Cancer Screening in Primary Care Settings

Recruiting now · Not applicable

Conditions studied: Uterine Cervical Neoplasms

In brief

Primary objective of the study is to determine the extent that offering of self-sampling in addition to clinician-sampling Human Papillomavirus (HPV) DNA testing will increase detection of HPV DNA through an increase in uptake rates of cervical cancer screening as compared to offering clinician-sampling HPV DNA testing alone. The hypothesis is that offering additional self-sampling will increase the detection of high-risk HPV DNA by at least 7.7%.

Key facts

Study ID

NCT06528184

Run by

National Healthcare Group Polyclinics

People needed

650

Starts

2024-08-05

Expected to finish

2026-12-01

Last updated by the study team

2025-02-10

Who can join

Age: 30 and older, up to 69. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• 30-69 years old female Singapore citizens
• Due for cervical cancer screening
• Engaged in sexual intercourse before
• Able to give informed consent
• Able to read and communicate in English, Chinese or Malay

You may not qualify if…

• Virgo intacta
• Pregnancy
• History of cervical cancer, precancerous cervical lesions and total hysterectomy

Where it is running

• National Healthcare Group Polyclinics — Singapore, Singapore, Singapore (enrolling)

Full record on ClinicalTrials.gov

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