A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)
Recruiting now · Phase 2
Conditions studied: T-cell Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
In brief
The T-RRex study evaluates the efficacy of WU-CART-007 for patients with Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL)/Lymphoblastic Lymphoma (LBL) and to WU-CART-007 as a therapy to induce complete Minimum Residual Disease (MRD) negative response
Key facts
- Study ID
- NCT06514794
- Run by
- Allotera Therapeutics
- People needed
- 125
- Starts
- 2025-01-31
- Expected to finish
- 2028-12-30
- Last updated by the study team
- 2026-08-06
Who can join
Age: 1 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- City of Hope — Duarte, California, United States (enrolling)
- Children's Hospital Los Angeles — Los Angeles, California, United States (enrolling)
- Colorado Blood Cancer Institute — Denver, Colorado, United States (enrolling)
- Children's National Hospital — Washington D.C., District of Columbia, United States (enrolling)
- H. Lee Moffitt Cancer Center and Research Institute Hospital — Tampa, Florida, United States (enrolling)
- Children's Hospital of Atlanta — Atlanta, Georgia, United States (enrolling)
- Washington University Saint Louis — St Louis, Missouri, United States (enrolling)
- Oncology Hematology Care — Cincinnati, Ohio, United States (enrolling)
- Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States (enrolling)
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States (enrolling)
- TriStar Bone Marrow Transplant / Sarah Cannon Transplant & Cellular Therapy — Nashville, Tennessee, United States (enrolling)
- MD Anderson Cancer Center — Houston, Texas, United States (enrolling)
- Sarah Cannon Transplant and Cellular Therapy Methodist Hospital — San Antonio, Texas, United States (enrolling)
- Sarah Cannon, Virginia Oncology Associates — Norfolk, Virginia, United States (enrolling)
- Seattle Children's Hospital — Seattle, Washington, United States (enrolling)
- Peter Mac Callum Cancer Institute — Melbourne, Victoria, Australia (enrolling)
- Royal Children's Melbourne — Melbourne, Victoria, Australia (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.