Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot Study
Stopped early · Not applicable
Conditions studied: Vaping Teens, Healthy Volunteers
In brief
The purpose of this translational bench-to-bedside study is to examine the neurobiological effects of an evidence-based technology-delivered mindfulness training (MT) program on vaping-related rsFC alterations in hippocampal networks and testing whether changes in rsFC ((Delta)rsFC) in these networks predict reduction in tobacco vaping behaviors in adolescents. The study also aims to test the accessibility and feasibility of using this mindfulness-based stress reduction (MBSR) platform as an implementation for widespread MT in adolescents.
Key facts
- Study ID
- NCT06503159
- Run by
- National Institute on Drug Abuse (NIDA)
- People needed
- 14
- Starts
- 2025-05-07
- Expected to finish
- 2025-09-11
- Last updated by the study team
- 2026-02-27
Who can join
Age: 13 and older, up to 18. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- An individual who meets any of the following criteria will be excluded from participation in this study based on self and or parent-report unless otherwise noted:
- Vaping or Non-Vaping Group:
- Chronic medical conditions associated with cerebral blood flow abnormalities per PI/MAI determination after review of the medical history.
- Neurological conditions that may interfere with MRI data quality per PI/MAI determination after review of the medical history.
- Neurodevelopmental disorders that are likely to significantly affect data in the judgment of the MAI/PI
- Non-penetrating traumatic brain injury with loss of consciousness > 30 minutes or significant sequelae persisting longer than two weeks or any penetrating traumatic brain injury.
- Changing dose of psychotropic medication in past three months
- Current regular meditation or yoga practice averaging >10 min/day for >2 days per week
- Pregnancy, self-report upon protocol entry, but by urine test prior to MRI scan.
Where it is running
- National Institute on Drug Abuse — Baltimore, Maryland, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.