Effort During Resistance Training in Type 2 Diabetes

Running, not enrolling · Not applicable

Conditions studied: Type2 Diabetes Mellitus

In brief

In this study the primary aims are to investigate the effect of resistance exercise training with different degrees of effort on glycemic control and psychological variables in individuals living with type 2 diabetes mellitus. As a secondary aim, investigate adherence and dropout rates and reasons for dropping out and adhering or not to the protocols.

Key facts

Study ID

NCT06497842

Run by

University of New Mexico

People needed

48

Starts

2024-09-10

Expected to finish

2026-07-30

Last updated by the study team

2026-06-10

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Living with type 2 diabetes mellitus

You may not qualify if…

• Have a significant cognitive impairment,
• Are non-ambulatory,
• Have lower extremity amputation,
• Have renal failure,
• Have liver disease,
• Have uncontrolled hypertension (>160 mmHg systolic and/or >100 mmHg diastolic),
• Have unstable cardiovascular disease,
• Have a history of severe cardiovascular problems,
• Have decompensated heart failure,
• Have uncontrolled arrhythmias,
• Have severe pulmonary hypertension (mean pulmonary arterial pressure >55 mm Hg),
• Have severe and symptomatic aortic stenosis,
• Have acute myocarditis, endocarditis, or pericarditis,
• Have aortic dissection,
• Have Marfan syndrome,
• Have unrepaired aortic aneurysm,
• Have proliferative diabetic retinopathy,
• Have rapidly progressive terminal illness,
• Are unable to perform resistance exercise to due preexisting musculoskeletal conditions (e.g., joint pain, chronic injury or tendinopathy),
• Are under biguanide (metformin) treatment, but are taking for less than 3 months,
• Have taken drugs known to increase the risk of tendon disorders (e.g., tendinopathy and tendon rupture) within the last 6 months. These drugs include, but may not be limited to: fluoroquinolones, glucocorticoids, aromatase inhibitors, anabolic steroids, antiretrovirals, isotretinoin, cephalexin, rituximab, sitagliptin, cephalosporins, azithromycin, and sulfonamides.
• Are pregnant or trying to become pregnant during the study,
• Are prisoners,
• Are persons that require a legally authorized representative.
• Temporary exclusions include:

Where it is running

• UNM Exercise Physiology Lab — Albuquerque, New Mexico, United States

Full record on ClinicalTrials.gov

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