Incremental Vestibulo-ocular Reflex Adaptation as a Novel Treatment for Dizziness in People With Multiple Sclerosis
Recruiting now · Not applicable
Conditions studied: Multiple Sclerosis
In brief
The study aims to study the effects of a novel treatment for vestibular symptoms in people with multiple sclerosis. The main objective is to determine whether daily personalized gaze stabilization training is more beneficial than intermittent gaze stability training in people with multiple sclerosis.
Key facts
- Study ID
- NCT06495138
- Run by
- Emory University
- People needed
- 138
- Starts
- 2025-04-21
- Expected to finish
- 2027-03-01
- Last updated by the study team
- 2025-07-16
Who can join
Age: 18 and older, up to 89. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Neurologist-confirmed diagnosis of primary progressive or relapsing and remitting MS per The 2017 Revision of the McDonald Criteria and the Magnetic Resonance Imaging in MS, or a healthy volunteer without a diagnosis of multiple sclerosis or any related neurological conditions
- Fluent in speaking and understanding English
- Subjects with multiple sclerosis have self-reported vestibular symptoms of dizziness, imbalance, and/or a history of at least two falls in the prior 12 months
You may not qualify if…
- Clinically isolated syndrome or radiologically isolated syndrome.
- Worsening MS symptoms during the prior 60 days
- Immunotherapy change in the prior 60 days
- Self-reported cognitive impairment that limits independence with basic and instrumental activities of daily living
- Systolic blood pressure > 180 mmHg and/or diastolic blood pressure > 90 mmHg at rest
- Static visual acuity with correction of worse than 1.0 logMAR
- Manifest ocular misalignment ≥ 5 diopters (e.g., tropia, lazy eye, strabismus}
- Convergence insufficiency
- Intra-nuclear ophthalmoplegia
- Vestibular Migraine
- Major orthopedic conditions that limit cervical spine range of motion or that alter walking
- Self-reported current or potential for pregnancy during enrollment
- Ongoing participation in vestibular rehabilitation for dizziness
Where it is running
- Emory Univeristy — Atlanta, Georgia, United States (enrolling)
Full record on ClinicalTrials.gov
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