Positive Minds Strong Joints for Knee Osteoarthritis

Recruiting now · Not applicable

Conditions studied: Osteoarthritis, Knee

In brief

The aim of this research study is to test the feasibility of a physical and mental health intervention (Positive Minds, Strong Joints or PMSJ) for Black adults with knee osteoarthritis (OA).

Key facts

Study ID

NCT06493903

Run by

Boston University Charles River Campus

People needed

40

Starts

2025-02-17

Expected to finish

2026-12-30

Last updated by the study team

2025-05-16

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age≥50
• BMI ≤ 40 kg/m2
• Self-identify as Black (including African American)
• Knee pain ≥4/10 on a 11 numeric scale over the past week
• Scored 5 or more on either the Patient Health Questionnaire (PHQ-9) and/or the Generalized Anxiety Disorder 7-item Scale (GAD-7)
• Can speak and understand English at a sufficient level to understand the study procedures and informed consent
• Available for study duration
• Able to attend remote sessions

You may not qualify if…

• Knee, hip or ankle replacement
• Intra-articular corticosteroid or hyaluronic acid knee injection within 3 months
• Knee surgery within past 6 months
• Currently receiving or received within 3-months any PT for knee OA
• Currently receiving or received within 3 months any mental health intervention (excluding pharmacologic treatments)
• Planning to initiate physical therapy for joint or low back pain in the next 3months
• Planning to initiate any mental health treatment (excluding pharmacologic treatments) in the next 1 month.
• Systemic inflammatory arthritis (e.g., rheumatoid arthritis)
• Neurologic conditions (e.g., stroke, Parkinson's disease, etc.)
• Contraindications to starting an exercise program.
• Suspected substance abuse
• Lack capacity to consent
• Pregnancy (self-report)
• Participation in another clinical trial for any joint or muscle pain
• Planning for a major surgery in the next 6 months
• Having high risk mental health symptoms (active suicidality, bipolar disorder, mania, psychosis, schizophrenia)
• Receiving chemotherapy or radiation therapy for cancer (except non-melanoma skin cancer)

Where it is running

• Boston University — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.