Online Interplay Between Deciding and Acting With Mild Cognitive Impairment

Completed · Not applicable

Conditions studied: Mild Cognitive Impairment

In brief

The investigators aim to understand the interplay and neural structures involved with decision--making and movement for participants with mild cognitive impairment. Rapidly deciding and acting becomes bottlenecked with mild cognitive impairment and Alzheimer's, leading to detrimental outcomes such as falling and car crashes. The investigators work will have a tangible impact by discovering sensitive biomarkers to detect disease onset and pave the way for informed and effective neurorehabilitation.

Key facts

Study ID

NCT06493422

Run by

University of Delaware

People needed

41

Starts

2025-01-28

Expected to finish

2026-06-30

Last updated by the study team

2026-07-06

Who can join

Age: 45 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• age 45 - 90 years
• Perfect or corrected vision
• Ability to reach
• Neurotypical Age-Matched control participants - No history of neurological disorders or injury.
• Mild Cognitive Impairment participants - clinical diagnosis of amnestic mild cognitive impairment.

You may not qualify if…

• Any injury or condition that impacts reaching
• Traumatic brain injury, such as concussion, in the last 6 months.
• Neurotypical Age-Matched control participants: Modified Telephone Interview for Cognitive Status (TICS-m) score < 34
• Mild Cognitive Impairment participants: Modified Telephone Interview for Cognitive Status (TICS-m) score > 34
• Mild Cognitive Impairment participants: Mini-Mental State Examination Second Edition (MMSE-2) score < 21.

Where it is running

• University of Delaware — Newark, Delaware, United States

Full record on ClinicalTrials.gov

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