Noninvasive Spinal Stimulation to Restore Hand Function in Children With Spinal Cord Injury
Enrolling by invitation · Not applicable
Conditions studied: Spinal Cord Injury Cervical
In brief
The main goal of this pilot study is to find the best ways to use transcutaneous spinal cord stimulation (scTS) to improve hand function in children with spinal cord injuries (SCI). The investigators will start by exploring the best places and strengths for applying scTS on the neck, the added benefits of applying scTS on the lower back (T11-T12), and comparing the effects of using activity based upper extremity training (a control treatment) alone versus combining it with scTS to help children with chronic SCI regain hand function.
Key facts
- Study ID
- NCT06489106
- Run by
- University of Louisville
- People needed
- 10
- Starts
- 2025-06-13
- Expected to finish
- 2027-07-31
- Last updated by the study team
- 2026-02-18
Who can join
Age: 7 and older, up to 12. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- For aim 1 and 2, 10 participants with SCI:
- age 7-12 years;
- chronic (>6 months), acquired upper motor neuron SCI;
- cervical SCI at or above C8 neurological level with motor score of 1-3 for finger flexors
- Pediatric Neurorecovery scale score of ≥2B and ≤ 4C for impaired grip
- For Aim 3, 4 participants with SCI who:
- complete aim 1 and 2;
- consent/assent for aim 3
- demonstrate a minimum of 10% increase in HG force with scTS (aim1-2)
- confirmed volitional activation in hand muscles during hang grip assessment without scTS
You may not qualify if…
- For all 3 aims will include:
- Botox use within past 3 months (for upper or lower extremity);
- current oral baclofen (or pump);
- musculoskeletal impairment limiting range of motion;
- unhealed fracture or other medical condition limiting participation in AB-UET;
- etiology of spina bifida;
- total ventilator dependence.
Where it is running
- Kentucky Spinal Cord Injury Research Center — Louisville, Kentucky, United States
Full record on ClinicalTrials.gov
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