Human Research Program Flight Thigh Cuff

Enrolling by invitation · Not applicable

Conditions studied: Healthy

In brief

Venoconstrictive Thigh Cuffs (VTC) are being evaluated to determine the effectiveness at reversing the headward fluid shift that occurs during weightlessness. If successful, future studies may be done to implement these as a CM to SANS. To support this effort, participants will participate in 2 preflight study sessions consisting of a VTC fit check and a baseline data collection without and with the VTC donned. Participants will also participate in 3 inflight study sessions: a VTC fit check on flight day 30 (FD30) and two separate data collection sessions on flight day 45 (FD45) and 45 days before landing (R-45). During the two in-flight data collection days, participants will be studied before and for up to 6 hours after donning the VTC.

Key facts

Study ID

NCT06476106

Run by

National Aeronautics and Space Administration (NASA)

People needed

10

Starts

2023-03-24

Expected to finish

2030-05-14

Last updated by the study team

2025-04-01

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Astronauts participating in missions that are ≥2 months

You may not qualify if…

• Having known allergies to proparacaine hydrochloride ophthalmic solution precludes participation in this study
• Use of ethinyl estradiol Combined Oral Contraceptive (COC) pills precludes participation in this study
• Having increased risk of venothromboembolism (VTE) based on preflight thrombosis/clotting related biomarkers precludes participation in this study

Where it is running

• Johnson Space Center, National Aeronautics and Space Administration — Houston, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.