Centella Asiatica in Older Adults

Completed · Not applicable · Has a placebo group

Conditions studied: Endothelial Dysfunction

In brief

The purpose of this study is to determine the effects of a dietary supplement containing centella asiatica on on vascular endothelial function in older adults.

Key facts

Study ID

NCT06472791

Run by

National University of Natural Medicine

People needed

23

Starts

2025-02-01

Expected to finish

2025-12-31

Last updated by the study team

2026-07-01

Who can join

Age: 50 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• ● Age 50 through 85, male or female
• Sufficient proficiency in English to understand study purpose and directions
• Willing and able to give informed consent
• Able to follow protocol and attend visits

You may not qualify if…

• History of myocardial infarction, known coronary or carotid disease, or heart failure
• History of stroke, Parkinson's disease, dementia, or other major CNS disorders
• History of hepatic disease (e.g. hepatitis, cirrhosis)
• Recent/recurring history of severe life-threatening medical conditions (e.g. cancer, except non-melanoma skin cancers)
• Active major infectious disease (e.g. pneumonia)
• Heavy alcohol use (15 drinks or more per week for men or 8 drinks or more per week for women) or substance use disorder
• Current use of any medication typically used to treat hypertension or lower blood pressure (e.g. beta-blockers, ACE inhibitors)
• Current use of any medication typically used to prevent the coagulation of blood (e.g. warfarin (Coumadin))
• Chronic NSAID use (>3 times a week for more than 3 months)
• Current use of any medication or supplement typically used as a sedative (e.g. zolpidem (Ambien), benzodiazepines (Valium, Xanax), valerian root)
• Dietary supplements for improving nitric-oxide synthesis (e.g. L-arginine, L-citrulline)
• Current use of any medication typically used to control hypoglycemia (e.g. biguanides (Metformin))
• Current use of any medication typically used for erectile dysfunction (e.g. sildenafil (Viagra), tadalafil (Cialis))
• Pregnant, nursing, or planning a pregnancy within the next 6 weeks
• Open skin rashes and sores that may interfere with the placement of sensors

Where it is running

• Helfgott Research Institute — Portland, Oregon, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.