Development of Electroencephalography (EEG) and Magnetoencephalography (MEG) Source Reconstruction With Fast Multipole Method

Recruiting now · Not applicable

Conditions studied: Healthy

In brief

The goal of this clinical trial is to learn if an advanced 256 dry electrode EEG cap augmented with MEG readings and coupled with a new high-resolution fast brain modeling software gives a better EEG and MEG source localization in real time. The main questions it aims to answer are: * Does the testbed better localize brain sources for finger movement? * Does the testbed better localize brain sources for median nerve stimulation? * Does the testbed better localize brain sources for speech processing? * Researchers will compare the predicted cortical locations with MEG data and known anatomical locations of the neuronal generators. Participants will: * Undergo Magnetic Resonance Imaging (MRI) scans for brain and head model creation * Undergo three different EEG tests * Undergo three different MEG tests

Key facts

Study ID

NCT06471244

Run by

Worcester Polytechnic Institute

People needed

30

Starts

2025-01-01

Expected to finish

2027-04-01

Last updated by the study team

2025-05-28

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age at least 18 and less than 66 years
• Normal hearing and (corrected) vision
• Able to understand and give informed consent

You may not qualify if…

• Cardiac pacemaker or pacemaker wires; neurostimulators; implanted pumps
• Metal in the body (rods, plates, screws, shrapnel, dentures, IUD) or metallic particles in the eye
• Surgical clips in the head or previous neurosurgery
• Any magnetic particles in the body
• Cochlear implants
• Prosthetic heart valves
• History of skull injury or defects
• Significant claustrophobia; Ménière's disease
• Pregnancy, breast feeding
• Neurological or psychiatric diagnoses or medications influencing brain function
• Current substance abuse (exception: concurrent nicotine use is allowed)
• Failure to perform the behavioral tasks or psychological evaluation tests
• Prisoners

Where it is running

• Technical University Ilmenau — Ilmenau, Germany (enrolling)
• Max-Planck-Institut für Kognitions- und Neurowissenschaften [Cognitive and Neuroscience] — Leipzig, Germany (enrolling)

Full record on ClinicalTrials.gov

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