Older People's Neurocognitive Recovery After Cardiac Surgery
Recruiting now
Conditions studied: Postoperative Cognitive Dysfunction, Postoperative Recovery, Cardiac Surgery
In brief
Society is aging and advantages in anesthesia and surgery allow more complex interventions in older persons. Old age is a significant risk factor for the development of postoperative neurocognitive decline characterized by a gradual decrease in performance in several cognitive domains such as memory, attention, information processing, and executive functions, leading to problems with performing daily activities and maintaining independence and postoperative complications. The purpose of this study is to measure older persons' postoperative neurocognitive function, to detect neurocognitive decline, and to identify risk factors and difficulties in daily living as well as explore close relatives' experiences of it. We will include 220 participants ≥65 years of age undergoing planned cardiac surgery. Cognitive symptoms and signs and neurocognitive function will be assessed up to 6 months after surgery. Risk/affected factors such as delirium, functional status, recovery, depression, and healthcare-related quality of life, as well as close relative's experiences and burden, will be measured. The results will have immediate relevance for a substantial number of older persons undergoing surgery, and their close relatives, by enhancing knowledge about postoperative cognitive decline and recovery, and subsequently identifying what support needs to be implemented.
Key facts
- Study ID
- NCT06469515
- Run by
- Karolinska Institutet
- People needed
- 220
- Starts
- 2024-11-01
- Expected to finish
- 2027-12-01
- Last updated by the study team
- 2024-11-07
Who can join
Age: 65 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Scheduled for elective or urgent open-heart surgery or minimally invasive cardiac surgery
- Resident in the area/region for the current thoracic clinic
- Able to read and understand Swedish
You may not qualify if…
- Physical, mental, and cognitive difficulties that prevent the individual from completing the cognitive tests
- Undergone surgery within the last 6 months
Where it is running
- Sahlgrenska University Hospital — Gothenburg, Sweden (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.